Data on file, Pet Owner Quantitative Market Research, 2013, Zoetis Inc.Treatment of canine atopic dermatitis: 2015 updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA). Olivry T, DeBoer DJ, Favrot C, et al for the International Committee on Allergic Diseases of Animals.Current understanding of the pathophysiologic mechanisms of canine atopic dermatitis. Marsella R, Sousa CA, Gonzalez AJ, Fadok VA.Effects of cetirizine in dogs with chronic atopic dermatitis: a randomized, double blind, placebo-controlled trail. Data on file, APOQUEL/CYTOPOINT Vet Tracker Wave 13, 2020, Zoetis Inc.Data on file, APOQUEL/CYTOPOINT Pet Tracker Wave 9, 2021, Zoetis Inc.ZMR: GAH-284 Unique Patients Since Launch with Growth Rate June 2022.Oclacitinib (APOQUEL ®) is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Gonzales AJ, Bowman JW, Fici G, et al.Long-term compassionate use of oclacitinib in dogs with atopic and allergic skin disease: safety, efficacy and quality of life. Cosgrove SB, Cleaver DM, King VL, et al.Vetstreet Pruritus Protection Trend, July 2021 Monthly Report: Market Share of Unique Pruritus patients.Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis. Cosgrove SB, Wren JA, Cleaver DM, et al.Efficacy of oclacitinib (Apoquel ®) compared with prednisolone for the control of pruritus and clinical signs associated with allergic dermatitis in client-owned dogs in Australia. Gadeyne C, Little P, King VL, Edwards N, Davis K, Stegemann MR.*Based on survey data from veterinarians (n=251) and pet owners (n=552). INDICATIONS: Control of pruritus (itching) associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age. Apoquel has been used safely with many common medications including parasiticides, antibiotics and vaccines. Most common side effects are vomiting and diarrhea. Do not use in breeding, pregnant, or lactating dogs. Apoquel has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. Apoquel may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Do not use Apoquel in dogs less than 12 months of age or those with serious infections. IMPORTANT SAFETY INFORMATION: See Prescribing Information.
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